Psychiatric drugs can cause permanent biological changes, dulled feelings and hamper recovery, researcher says


Psychotropics can cause structural brain remodeling that negatively affects emotions and other aspects of mental function and may become irreversible.

Doctor holding pills

Psychotropics act primarily to suppress psychological processes. Suppression is essential to their effect, not a side effect.

Girl sitting on the floor with pills

With the continued use of psychotropic drugs, patients become passive and unable to understand and deal with the causes and consequences of their situation.

Dr. Thomas Szasz

Dr. Thomas Szasz, co-founder of the Citizens Commission on Human Rights, was a renowned mental health human rights advocate.

The use of psychotropic drugs can lead to “structural brain remodeling” which dulls emotions and results in “sunset patients”.

Psychotropics block the expression of feelings, affect the process of problem solving and make the person passive.

— Jose Luis Turabian, MD, Ph.D.

WASHINGTON, DC, USA, January 12, 2022 / — A new research paper examines the neurobiological changes caused by mind-altering drugs, which ironically prolong mental symptoms and hinder their resolution, and warns that these adverse effects can become permanent over time.

Writing in the Journal of Addictive Disorders and Mental Health, Jose Luis Turabian, MD, Ph.D. reviews the medical literature and refers to his clinical experience to support view that psychotropic drugs can lead to “structural brain remodeling” that negatively affects emotions and other aspects of mental function and may become irreversible.

“Psychotropics produce functional changes in thoughts, feelings, and behaviors that, over time, [become] structural/organic and permanent,” he writes.

The drugs dampen human emotions and cloud cognitive function, making it harder for patients to deal with the underlying issues leading to the mental symptoms, according to Turabian. “Psychotropics block the expression of feelings, affect the problem-solving process and make the person passive,” he writes.

He explains that psychotropics work primarily to suppress psychological processes and that “suppression is essential to their effect, not a side effect.”

“Neuroleptics [antipsychotic drugs] suppressing motivation and imagination and interfering with the regulation of body form and movement; benzodiazepines suppress behavioral control and discrimination; selective serotonin reuptake inhibitor [SSRI antidepressants] remove eroticism [sexual] core,” he says.

The risk of permanent harm to patients increases with continued use of the drugs, and he notes that longer-term use has not been well studied. “Overall, there is no good literature on the long-term impact of psychotropic drugs used to treat symptoms in adults,” he writes.

What is observable over time with continued use of mood-altering drugs are “passive patients, unable to understand and confront the causes and consequences of their situation,” he says. “These are irrecoverable patients.”

For this risk of lifelong adverse effects, the benefits of psychiatric drugs for patients may be minimal or non-existent. Turabian notes that meta-analyses of clinical trials suggest that “psychotropic drugs are only marginally effective compared to placebos”, and only if one ignores “a profound publication bias that increases their apparent efficacy”. Publication bias occurs when unfavorable results of clinical trials are not published.

Other research has also shown that the adverse effects of psychiatric drugs on the body may outweigh any potential benefit, as in the case of the new generation of SSRI antidepressants. It is not known how these antidepressants work. What we do know is that drugs disrupt the body’s normal biochemistry in ways that are not fully understood.

A team of researchers led by Paul W. Andrews, Ph.D., professor of psychology and evolutionary biologist, analyzed previous studies to determine the overall physical impact of SSRI antidepressants on the human body. SSRI antidepressants target serotonin, a neurotransmitter that through the evolutionary adaptations of the human body has come to regulate emotions, development, nerve cells, the clotting process, attention, electrolyte balance, and reproduction.

Researchers’ discovery, published in Frontiers in Psychology, was clear: “Our review supports the conclusion that antidepressants generally do more harm than good by disrupting a number of serotonin-regulated adaptive processes.”

“It is widely accepted that antidepressant drugs are both safe and effective; however, this belief was formed in the absence of adequate scientific verification,” they wrote. “The current weight of evidence suggests that, in general, antidepressants are neither safe nor effective; they seem to do more harm than good.

Psychiatrist Peter Breggin, MD, describe antidepressants as neurotoxic because they impair and disrupt brain function, causing abnormal thinking and behaviors that include anxiety, irritability, hostility, aggression, loss of judgment, impulsiveness and mania, which can lead to violence and suicide.

Antidepressants can also take away the joy of living. “Over the long term, antidepressants, like almost all psychiatric drugs, lead to apathy, indifference, and lack of attention,” Breggin writes. “Emotional life is dull and relationships lack empathy and love.”

WARNING: Anyone wishing to discontinue or alter the dose of any psychiatric medication is cautioned to do so only under the supervision of a physician due to potentially dangerous withdrawal symptoms.

The Citizens Commission on Human Rights continues to educate consumers about the serious adverse effects of psychiatric medications so that they can make informed decisions before starting or stopping medication. CCHR also continues to press government mental health and drug enforcement agencies to issue new warnings about these risks.

CCHR was co-founded in 1969 by members of the Church of Scientology and the late psychiatrist and humanitarian Thomas Szasz, MD, recognized by many scholars as the most authoritative critic of modern psychiatry, to eradicate abuses and restore human rights and dignity in mental health. health. Since then, CCHR has helped secure over 180 laws that protect mental health patients.

CCHR’s National Affairs Office in Washington, DC, has advocated for mental health rights at the state and federal levels. CCHR’s traveling exhibit, which has toured 441 major cities around the world and educated more than 800,000 people about the history of abusive psychiatric practices so far, was shown in Washington, D.C., at the Congressional Black Caucus Foundation Annual Legislative Caucus and other locations. .

Anne Goedeke
Citizens Commission for Human Rights, Office of National Affairs
+1 202-349-9267
write to us here

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